Addison’s Disease in Dogs: Symptoms, Treatment & Prevention

Addison’s Disease in Dogs: Symptoms, Treatment & Prevention

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Jan 17, 2024

  • Addison’s disease in dogs is a hormone disorder where important hormones in the body are not being produced at adequate levels.
  • Addisonโ€™s in dogs is also known as hypoadrenocorticism.
  • The most common symptoms of Addisonโ€™s disease in dogs include lethargy, vomiting, and diarrhea.
  • Addisonโ€™s disease is diagnosed by running a blood test called the ACTH stimulation test.

  • The treatment for Addisonโ€™s disease includes hormone replacement therapies through injections and oral medications prescribed by your veterinarian.

What is Addison’s disease in dogs?

Addisonโ€™s disease, also known as hypoadrenocorticism, is a disease in which hormone production is decreased. Many hormones are produced by the adrenal glands. They are two small organs that live inside your dogโ€™s belly near the kidneys. These hormones are important for normal body functions and promote the overall health of your dog. With Addisonโ€™s disease in dogs, there are not enough hormones being produced by the adrenal glands.

What triggers Addison’s disease in dogs?

Addisonโ€™s in dogs occurs when the adrenal glands fail to produce the hormones that the body needs. This is usually an immune-mediated process, meaning the body thinks that the adrenal glands are a foreign substance, so the body will attack itself, which will destroy the adrenal glands. Without enough hormones in your dogโ€™s system, they can become very sick. Sometimes, Addisonโ€™s disease can occur when treating Cushingโ€™s disease in dogs, as the medication for this disease can affect the production of hormones.

Addison's disease in dogs: symptoms, treatment & prevention

What are the symptoms of Addison’s disease in dogs?

The symptoms of Addison’s disease in dogs are often vague, non-specific, and can wax and wane. As symptoms can often be non-specific, Addisonโ€™s in dogs can be frequently mistaken for other diseases such as kidney failure, cancer, and pancreatitis. Because of this, Addisonโ€™s disease is also known as the great pretender. Many symptoms of Addison’s disease in dogs get worse during times of stress.

According to the AKC, the most common symptoms of Addisonโ€™s disease in dogs symptoms include:

  • Decreased appetite
  • Vomiting
  • Diarrhea
  • Losing weight
  • Lethargy
  • Increased drinking and urination
  • Shaking

Is Addison’s disease common in dogs?

Addisonโ€™s disease is an uncommon disease in dogs. Addisonโ€™s dogs usually appear in middle-aged dogs at an average age of 3 to 7 years. This disease can affect almost any age of a dog and has even been reported in dogs as young as 4 months of age and as old as 14 years of age. Female dogs are at a higher risk for developing Addisonโ€™s disease, and certain dog breeds seem to be more prone to developing Addisonโ€™s disease.

What dog breeds are prone to Addison’s disease?

Addisonโ€™s disease in dogs may have some genetic components. Certain dog breeds have a higher risk of developing Addisonโ€™s disease. Researchers from Animal Medical Center found that the following dog breeds may be more prone to developing Addisonโ€™s disease:

What is atypical Addison’s disease in dogs?

Atypical Addisonโ€™s disease occurs when only certain layers of the adrenal glands are destroyed. This means that the dog is still able to produce certain hormones but not others. This can result in varying symptoms that may make Addisonโ€™s disease a little more difficult to diagnose. Dogs with atypical Addisonโ€™s disease usually have intermittent symptoms of diarrhea, decreased appetite, and vomiting.

How is Addisonโ€™s disease in dogs diagnosed?

If you suspect your dog has Addisonโ€™s disease, I recommend contacting your veterinarian as soon as possible. Your veterinarian may recommend x-rays and blood work to rule out other common conditions.

The blood work may have some findings that suggest Addisonโ€™s disease. If your veterinarian suspects Addisonโ€™s, they will likely recommend an ACTH stimulation test to diagnose Addisonโ€™s disease. The test will show if your dog has low levels of the hormone cortisol, which is suggestive of Addisonโ€™s disease.

Addison's disease in dogs: symptoms, treatment & prevention

What is the treatment for Addison’s disease in dogs?

The treatment for Addisonโ€™s disease is supportive care and hormone replacement therapy. Some dogs with Addisonโ€™s disease present extremely ill. These dogs will often need hospitalization and IV fluid replacement to balance your dogโ€™s electrolytes.

Your veterinarian will administer injectable hormones called desoxycorticosterone pivalate (DOCP) every 3 to 4 weeks. In addition, you will have to give your dog oral steroid hormones for the rest of their life. When your dog gets home from the vet hospital, you will want to ensure they have a comfortable and quiet recovery area, so check out this machine-washable cozy calming bed for dogs.

How much does it cost to treat Addison’s disease in dogs?

The treatment cost for Addisonโ€™s in dogs varies depending on several factors. If your dog is extremely ill and needs to be hospitalized, the bill could easily run into the thousands. According to Embrace Pet Insurance, the average cost to manage a dog with Addisonโ€™s can range from $50 to $200 monthly. This cost depends on your petโ€™s response to therapy and how often follow-up blood work needs to be performed. Your veterinarian will be able to give you a more accurate estimate of the cost of treatment for your dog.

What happens if you don’t treat Addison’s disease in dogs?

It can be fatal if you donโ€™t treat Addisonโ€™s in dogs. To function properly, the body needs hormones. Without hormone therapy, the electrolytes in your dogโ€™s system cannot be balanced. If the dog’s electrolytes become imbalanced, this can result in severe dehydration, fatal heart arrhythmias, shock, collapse, and even death.

How long can dogs live with Addison’s disease?

If caught early, before your dog is extremely ill, the prognosis for Addisonโ€™s disease in dogs is generally very good. There are effective and safe medications that can be used to manage Addisonโ€™s disease. These medications must be given for the rest of your dogโ€™s life. Often, dogs with Addisonโ€™s disease that are treated with lifelong hormone replacement therapy will die of some other cause.

Preventing Addisonโ€™s Disease in Dogs

Unfortunately, there are not effective options for preventing most cases of Addisonโ€™s disease in dogs. For the drug-induced Addisonโ€™s cases, it is essential to follow your veterinarianโ€™s instructions on administering medications. Always be monitoring for side effects of medications in your dog and alert your veterinarian if you notice anything unusual.

Multivitamins for Dogs

Enrich your dog’s daily routine with essential multivitamins tailored to support their overall health and vitality. Our carefully selected multivitamin supplements provide a comprehensive blend of key nutrients, including vitamins, minerals, and antioxidants, designed to address the specific health needs of dogs.

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  • Zesty Paws Multifunctional Bites are made with premium ingredients that support physical performance, antioxidants, hip and joint, heart, immune, skin, liver and gut health.
  • For animals with sensitive skin, this formula contains cod liver fish oil and vitamin E to help maintain normal moisture plus CoQ10 to help reduce oxidative stress.
  • Each dog chew features a premium form of MSM for muscular support, which works synergistically with glucosamine HCl and chondroitin sulfate for hip and joint support—plus, cod liver oil and B-complex vitamins support normal physical performance.
  • These chews also contain a six-strain gut health blend—with over 500 million CFU per chew—and a digestive health blend to promote gut flora while supporting normal bowel function for dogs.
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Alpha Paw Sale
author image

Dr. Addie Reinhard, DVM

Member of Alpha Pawโ€™s Board of Pet Experts

Dr. Addie Reinhard is an experienced companion animal veterinarian who lives in Lexington, KY with her husband, greyhound, and four cats. She graduated from the University of Tennessee College of Veterinary Medicine, and currently practices in the central Kentucky region. Dr. Addie has special interests in preventative care, dermatology, and diseases, and she enjoys creating helpful educational resources related to these topics to help pet parents keep their four-legged family members happy and healthy. We love Dr. Addieโ€™s passion for providing reliable veterinary insight and medical advice to help pet parents like us give their pups the happy & healthy lives they deserve!

Disclaimer

The medical, nutritional, or behavioral advice we provide is intended for informational and educational purposes only. Our editorial content is not a substitute for formal or personalized medical advice from a veterinary professional. Only board-certified veterinary specialists who have examined your pet should diagnose medical conditions, provide personalized treatment, or prescribe appropriate medication. For questions regarding your petโ€™s health, or if your pet is exhibiting signs of illness, injury, or distress, contact your veterinarian immediately. Never disregard professional medical advice or delay in seeking it because of something you have read on our site.

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