Addisonโs disease, also known as hypoadrenocorticism, is a disease in which hormone production is decreased. Many hormones are produced by the adrenal glands. They are two small organs that live inside your dogโs belly near the kidneys. These hormones are important for normal body functions and promote the overall health of your dog. With Addisonโs disease in dogs, there are not enough hormones being produced by the adrenal glands.
Addisonโs in dogs occurs when the adrenal glands fail to produce the hormones that the body needs. This is usually an immune-mediated process, meaning the body thinks that the adrenal glands are a foreign substance, so the body will attack itself, which will destroy the adrenal glands. Without enough hormones in your dogโs system, they can become very sick. Sometimes, Addisonโs disease can occur when treating Cushingโs disease in dogs, as the medication for this disease can affect the production of hormones.
The symptoms of Addison’s disease in dogs are often vague, non-specific, and can wax and wane. As symptoms can often be non-specific, Addisonโs in dogs can be frequently mistaken for other diseases such as kidney failure, cancer, and pancreatitis. Because of this, Addisonโs disease is also known as the great pretender. Many symptoms of Addison’s disease in dogs get worse during times of stress.
According to the AKC, the most common symptoms of Addisonโs disease in dogs symptoms include:
Addisonโs disease is an uncommon disease in dogs. Addisonโs dogs usually appear in middle-aged dogs at an average age of 3 to 7 years. This disease can affect almost any age of a dog and has even been reported in dogs as young as 4 months of age and as old as 14 years of age. Female dogs are at a higher risk for developing Addisonโs disease, and certain dog breeds seem to be more prone to developing Addisonโs disease.
Addisonโs disease in dogs may have some genetic components. Certain dog breeds have a higher risk of developing Addisonโs disease. Researchers from Animal Medical Center found that the following dog breeds may be more prone to developing Addisonโs disease:
Atypical Addisonโs disease occurs when only certain layers of the adrenal glands are destroyed. This means that the dog is still able to produce certain hormones but not others. This can result in varying symptoms that may make Addisonโs disease a little more difficult to diagnose. Dogs with atypical Addisonโs disease usually have intermittent symptoms of diarrhea, decreased appetite, and vomiting.
If you suspect your dog has Addisonโs disease, I recommend contacting your veterinarian as soon as possible. Your veterinarian may recommend x-rays and blood work to rule out other common conditions.
The blood work may have some findings that suggest Addisonโs disease. If your veterinarian suspects Addisonโs, they will likely recommend an ACTH stimulation test to diagnose Addisonโs disease. The test will show if your dog has low levels of the hormone cortisol, which is suggestive of Addisonโs disease.
The treatment for Addisonโs disease is supportive care and hormone replacement therapy. Some dogs with Addisonโs disease present extremely ill. These dogs will often need hospitalization and IV fluid replacement to balance your dogโs electrolytes.
Your veterinarian will administer injectable hormones called desoxycorticosterone pivalate (DOCP) every 3 to 4 weeks. In addition, you will have to give your dog oral steroid hormones for the rest of their life. When your dog gets home from the vet hospital, you will want to ensure they have a comfortable and quiet recovery area, so check out this machine-washable cozy calming bed for dogs.
The treatment cost for Addisonโs in dogs varies depending on several factors. If your dog is extremely ill and needs to be hospitalized, the bill could easily run into the thousands. According to Embrace Pet Insurance, the average cost to manage a dog with Addisonโs can range from $50 to $200 monthly. This cost depends on your petโs response to therapy and how often follow-up blood work needs to be performed. Your veterinarian will be able to give you a more accurate estimate of the cost of treatment for your dog.
It can be fatal if you donโt treat Addisonโs in dogs. To function properly, the body needs hormones. Without hormone therapy, the electrolytes in your dogโs system cannot be balanced. If the dog’s electrolytes become imbalanced, this can result in severe dehydration, fatal heart arrhythmias, shock, collapse, and even death.
If caught early, before your dog is extremely ill, the prognosis for Addisonโs disease in dogs is generally very good. There are effective and safe medications that can be used to manage Addisonโs disease. These medications must be given for the rest of your dogโs life. Often, dogs with Addisonโs disease that are treated with lifelong hormone replacement therapy will die of some other cause.
Unfortunately, there are not effective options for preventing most cases of Addisonโs disease in dogs. For the drug-induced Addisonโs cases, it is essential to follow your veterinarianโs instructions on administering medications. Always be monitoring for side effects of medications in your dog and alert your veterinarian if you notice anything unusual.
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The medical, nutritional, or behavioral advice we provide is intended for informational and educational purposes only. Our editorial content is not a substitute for formal or personalized medical advice from a veterinary professional. Only board-certified veterinary specialists who have examined your pet should diagnose medical conditions, provide personalized treatment, or prescribe appropriate medication. For questions regarding your petโs health, or if your pet is exhibiting signs of illness, injury, or distress, contact your veterinarian immediately. Never disregard professional medical advice or delay in seeking it because of something you have read on our site.